Esters (ethyl acetate and other aroma esters)

Aromatics and flavor compounds · 11 findings (9 positive, 2 negative)

What worked

IAH1 knockdown → mixed ethyl acetate production Positive
host K. marxianus · strain DU3 · Muñoz-Miranda LA 2024 · details
PDA1 knockdown + PDC1 overexpression → increases ethyl acetate titer Positive
host K. marxianus · Wei S 2024 · details
EAT1 truncation → increases ethyl acetate production Positive
host Escherichia coli · Kruis AJ 2020 · details
ATF1 overexpression → increases ester content in mezcal Positive
host K. marxianus · strain UMPe-1 · Campos-García J 2018 · details
EAT1 knockout → decreases ethyl acetate production Positive
host K. marxianus · Löbs AK 2018 · details
EAT1 knockout → decreases isoamyl acetate production Positive
host K. marxianus · Löbs AK 2018 · details
EAT1 knockout → decreases phenylethyl acetate production Positive
host K. marxianus · Löbs AK 2018 · details
EAT1 truncation → decreases ester biosynthesis Positive
host K. marxianus · Löbs AK 2018 · details
ACO2B knockdown + SDH2 knockdown + RIP1 knockdown + MSS51 knockdown → increases ethyl acetate productivity Positive
host K. marxianus · Löbs AK 2018 · 3.8-fold · details

EAT1 heterologous expression → no_effect ethyl acetate production Negative
host Clostridium autoethanogenum · Dykstra JC 2022 · < 0.01 mM · details
EAT1 truncation → no_effect specific enzyme activity Negative
host Escherichia coli · Kruis AJ 2020 · details