ADH2A knockout: succinic acid titer
Positive AI-extracted, curator-verified MARXBASE-R000061
| Gene | ADH2A Name without a genome identifier |
|---|---|
| Gene from | K. marxianus |
| Change | knockout |
| Effect | increases |
| Phenotype | succinic acid titer (product formation) |
| Class | Positive |
| Host | K. marxianus |
| Strain | YZH43 |
| Product | Succinic acid (Organic acids) |
Measured
| Value | 32.38 g/L |
|---|---|
| Size as written | 32.38 g/L |
| Metric | titer |
Conditions
| Temperature | 37 °C |
|---|---|
| Carbon source | glucose |
Changed together
- GPD1 knockout (MARXBASE-R000059)
- ACH1 knockout (MARXBASE-R000060)
- NDE1 overexpression (MARXBASE-R000062)
Evidence
Evidence sentences are not included in this release.
Paper
Development of a CRISPR/Cas12a genome editing toolbox in Kluyveromyces marxianus and its application in succinic acid biosynthesis.
Zha H; Li Y; Hu Z; Li J; Xie Y; Zhao M; Ren L; Zhang B
Synthetic and systems biotechnology 2026 · PubMed · DOI · PMC
Cite as: MarxBase result MARXBASE-R000061, release 1.0.