GPD1
Locus tag KLMA_10179 MARXBASE-G000028
11 findings (9 positive, 2 context-dependent).
| Organism | K. marxianus |
|---|
| Locus tag | KLMA_10179 |
|---|
| Identity method | name match |
|---|
| Confidence | high |
|---|
S. cerevisiae ortholog
| Gene | ID | Identity | Coverage | Rank | Confidence |
|---|
| GPD1 | YDL022W | 72.6% | 97.7% | 1 | high |
| GPD2 | YOL059W | 73.7% | 81.4% | 2 | medium |
Results
gene expression (2 context-dependent)
GPD1 deletion →
mixed GPD1 expression
∼ Context-dependent FPS1 deletion +
GPD1 deletion →
decreases GPD1 expression
∼ Context-dependent
product formation (8 positive)
GPD1 knockout +
ACH1 knockout +
ADH2A knockout +
NDE1 overexpression →
increases succinic acid titer
+ Positive GPD1 knockout +
ACH1 knockout +
ADH2A knockout +
NDE1 overexpression →
decreases glycerol production
+ Positive GPD1 knockout +
ACH1 knockout +
ADH2A knockout +
NDE1 overexpression →
decreases ethanol production
+ Positive GPD1 knockout +
ACH1 knockout +
ADH2A knockout +
NDE1 overexpression →
decreases acetate production
+ Positive GPD1 knockout →
decreases glycerol production
+ Positive GPD1 knockout →
decreases acetate production
+ Positive GPD1 knockout →
decreases glycerol byproducts
+ Positive GPD1 knockout →
decreases acetic acid byproducts
+ Positive
stress tolerance (1 positive)
GPD1 deletion →
decreases hyperosmotic stress tolerance
+ Positive