XYL2
Locus tag KLMA_70044 MARXBASE-G000134
8 findings (6 positive, 2 negative).
| Organism | K. marxianus |
|---|
| Locus tag | KLMA_70044 |
|---|
| Identity method | name match |
|---|
| Confidence | high |
|---|
S. cerevisiae ortholog
| Gene | ID | Identity | Coverage | Rank | Confidence |
|---|
| SOR1 | YJR159W | 66.7% | 99.2% | 1 | high |
| SOR2 | YDL246C | 66.7% | 99.2% | 2 | medium |
| XYL2 | YLR070C | 54.0% | 98.9% | 3 | medium |
Results
enzyme activity (1 positive, 1 negative)
XYL1 mutagenesis evolution +
XYL2 mutagenesis evolution →
no_effect xylose reductase activity
− Negative XYL2 mutagenesis evolution +
XYL1 mutagenesis evolution →
increases xylitol dehydrogenase activity
+ Positive
growth (1 positive, 1 negative)
XYL2 knockout →
no_effect growth in mannitol medium
− Negative XYL2 knockout →
decreases growth in sorbitol medium
+ Positive
product formation (4 positive)
XYL1 overexpression +
XYL2 overexpression +
XYL3 overexpression →
increases ethanol yield
+ Positive XYL1 mutagenesis evolution +
XYL2 mutagenesis evolution →
increases ethanol concentration from xylose
+ Positive XYL1 mutagenesis evolution +
XYL2 mutagenesis evolution →
increases ethanol production yield from xylose
+ Positive XYL2 knockout →
increases xylitol titer
+ Positive