MarxBaseK. marxianus metabolic engineering results

MED15 overexpression: xylitol titer

Positive AI-extracted, curator-verified MARXBASE-R000463

GeneMED15 Locus tag KLMA_20369
Gene fromK. marxianus
Changeoverexpression
Effectincreases
Phenotypexylitol titer (product formation)
Class Positive
HostK. marxianus
StrainYZB639
ProductXylitol (Sugar alcohols and polyols)
Condition tag46C_micro_oxygen

Measured

Value74.13 g/L
Size as written74.13 g/L with complete xylose consumption
Metrictiter

Conditions

Temperature46 °C
Mediummicro-oxygen
Oxygenmicroaerobic

Changed together

Evidence

Evidence sentences are not included in this release.

Paper

ROS signaling mediates aeration-dependent thermotolerance in Kluyveromyces marxianus for high-temperature xylitol production.
Hu Z; Li Y; Dong N; Zhao M; Gao B; Zhao J; Tao X; Ren L; Zhang B
Bioresource technology 2026 · PubMed · DOI

Cite as: MarxBase result MARXBASE-R000463, release 1.0.