SDH1 knockout: succinic acid production
Positive AI-extracted, curator-verified MARXBASE-R000049
| Gene | SDH1 Locus tag KLMA_20466 |
|---|---|
| Gene from | K. marxianus |
| Change | knockout |
| Effect | increases |
| Phenotype | succinic acid production (product formation) |
| Class | Positive |
| Host | K. marxianus |
| Strain | not stated |
| Product | Succinic acid (Organic acids) |
Measured
No quantified value stated.
Changed together
- SDH3 knockout (MARXBASE-R000050)
- SDH5 knockout (MARXBASE-R000051)
- SDH4A knockout (MARXBASE-R000052)
- SDH2 knockout (MARXBASE-R000053)
Evidence
Evidence sentences are not included in this release.
Paper
Development of a CRISPR/Cas12a genome editing toolbox in Kluyveromyces marxianus and its application in succinic acid biosynthesis.
Zha H; Li Y; Hu Z; Li J; Xie Y; Zhao M; Ren L; Zhang B
Synthetic and systems biotechnology 2026 · PubMed · DOI · PMC
Cite as: MarxBase result MARXBASE-R000049, release 1.0.