Engineering Kluyveromyces marxianus for 3-hydroxypropionic acid production at elevated temperature from Jerusalem artichoke tubers and crude glycerol.
Li J; Hu Z; Li Y; Zha H; Xie Y; Zhao M; Ren L; Zhang B
Synthetic and systems biotechnology 2026 · China · PubMed · DOI · PMC
Results (4 findings)
ADH2A deletion +
ACH1 deletion →
increases 3-HP titer
+ Positive GUT1 other +
GUT2 other +
GDH1 other +
DAK1 other →
increases glycerol utilization
+ Positive GUT1 other +
GUT2 other +
GDH1 other +
DAK1 other →
increases intracellular NADH supply
+ Positive UTR1 overexpression →
increases NADPH supply
+ Positive
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