Effect of a Novel Alpha/Beta Hydrolase Domain Protein on Tolerance of K. marxianus to Lignocellulosic Biomass Derived Inhibitors.
Wu D; Wang D; Hong J
Frontiers in bioengineering and biotechnology 2020 · China · PubMed · DOI · PMC
Results (7 findings)
YME knockout →
no_effect gene expression at transcriptional level
− Negative YME knockout →
decreases tolerance to lignocellulose-derived inhibitors
+ Positive YME knockout →
decreases mitochondrial membrane potential
+ Positive YME knockout →
increases plasma membrane permeability
+ Positive YME knockout →
increases ROS accumulation
+ Positive YME knockout →
decreases intracellular ATP, NAD and NADP concentration
+ Positive YME knockout →
decreases tolerance to ethanol, temperature and osmotic pressure
+ Positive
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