ADH3

Undetermined paralog MARXBASE-G000262

4 findings (4 negative).

Several K. marxianus loci carry this symbol. All candidate loci are recorded in gene_locus until the right one is determined (full text or supplement may be needed). Hint: KLMA_20158 (paper context).

K. marxianus has several copies of this gene and the papers do not say which one was used.

Candidate loci

Undetermined: the papers do not say which copy was used.

• KLMA_20158 – alcohol dehydrogenase ADH3 (annotation symbol matches; reciprocal best hit of S. cerevisiae ADH3; product shares alcohol, dehydrogenase with the S. cerevisiae ADH3 description; paper wording (PMID 19966463) shares adh3, dehydrogenase)
• KLMA_80306 – zinc-dependent alcohol dehydrogenase (annotation symbol matches; product shares alcohol, dehydrogenase with the S. cerevisiae ADH3 description; paper wording (PMID 19966463) shares dehydrogenase)

Results

cell physiology (1 negative)

• ADH3 knockout → increases ROS accumulation − Negative
  host K. marxianus · Lertwattanasakul N 2009 · details

enzyme activity (1 negative)

• ADH3 knockout → increases NADH dehydrogenase activity − Negative
  host K. marxianus · Lertwattanasakul N 2009 · details

growth (1 negative)

• ADH3 knockout → decreases growth on non-fermentable carbon sources − Negative
  host K. marxianus · Lertwattanasakul N 2009 · details

stress tolerance (1 negative)

• ADH3 knockout → increases H2O2 sensitivity − Negative
  host K. marxianus · Lertwattanasakul N 2009 · details