MarxBaseK. marxianus metabolic engineering results

QDR3 overexpression: fumaric acid titer

Positive AI-extracted, curator-verified MARXBASE-R000412

GeneQDR3 Locus tag KLMA_50233
Gene fromK. marxianus
Changeoverexpression
Effectincreases
Phenotypefumaric acid titer (product formation)
Class Positive
HostK. marxianus
Strainnot stated
ProductFumaric acid (Organic acids)

Measured

Value2.16 g L-1 (baseline 0.26 g L-1)
Size as writtenfrom 0.26 to 2.16 g L-1
Metrictiter

Changed together

Evidence

Evidence sentences are not included in this release.

Paper

Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus.
Thornbury M; Omran RP; Kumar L; Knoops A; Abushahin R; Whiteway M; Martin VJJ
ACS synthetic biology 2025 · PubMed · DOI

Cite as: MarxBase result MARXBASE-R000412, release 1.0.