ITR2 knockout: myo-inositol titer
Positive AI-extracted, curator-verified MARXBASE-R000382
| Gene | ITR2 Locus tag KLMA_80273 |
|---|---|
| Gene from | K. marxianus |
| Change | knockout |
| Effect | increases |
| Phenotype | myo-inositol titer (product formation) |
| Class | Positive |
| Host | K. marxianus |
| Strain | KM-JC4 |
| Product | Myo-inositol (Sugar alcohols and polyols) |
Measured
| Value | 80.7 g/L |
|---|---|
| Size as written | 80.7 g/L |
| Metric | titer |
Conditions
| Scale | bench bioreactor |
|---|---|
| Volume (L) | 5 |
| Carbon source | glucose and glycerol |
| Medium | 5 L bioreactor |
Changed together
- PGI1 knockout (MARXBASE-R000380)
- ZWF1 knockout (MARXBASE-R000381)
- MIOX5 knockout (MARXBASE-R000383)
Evidence
Evidence sentences are not included in this release.
Paper
Metabolic engineering of Kluyveromyces marxianus to produce myo-inositol from starch.
Lan Q; Wu P; Yu Y; Zhou J; Lu H
Bioresource technology 2025 · PubMed · DOI
Cite as: MarxBase result MARXBASE-R000382, release 1.0.