MarxBaseK. marxianus metabolic engineering results

HRD3 deletion: secretion of heterologous proteins

Positive hand-curated (gold) MARXBASE-R000011

GeneHRD3 Locus tag KLMA_70251
Gene fromK. marxianus
Changedeletion
Effectincreases
Phenotypesecretion of heterologous proteins (protein production)
Class Positive
HostK. marxianus
Strainnot stated
ProductSecreted enzyme (Enzymes)
Condition tagdeletion

Measured

Size as written+43% endoxylanase, +28% glucanase activity (fed-batch, vs wild type)

Evidence

Evidence sentences are not included in this release.

Paper

Characterization and modulation of endoplasmic reticulum stress response target genes in Kluyveromyces marxianus to improve secretory expressions of heterologous proteins.
Shi T; Zhou J; Xue A; Lu H; He Y; Yu Y
Biotechnology for biofuels 2021 · PubMed · DOI · PMC

Cite as: MarxBase result MARXBASE-R000011, release 1.0.