CBS 6556
MARXBASE-S000008
Other designations
ATCC 26548, KCTC 17555, NCYC 2597, NRRL Y-7571
Includes results recorded under derived strains: KCTC17555ΔURA3.
Results (12 findings)
PGK promoter swap →
decreases alpha-galactosidase production
− Negative GAL7 promoter swap →
decreases alpha-galactosidase production
− Negative INU1 truncation →
decreases alpha-galactosidase production level
− Negative INU1 truncation →
decreases alpha-galactosidase secretion efficiency
− Negative ARO4 overexpression +
PHA2 overexpression +
ARO7 overexpression →
increases 2-PE production
+ Positive XYL1 copy number increase →
increases xylitol production
+ Positive XYL1 copy number increase →
increases xylose reductase activity
+ Positive XYL1 copy number increase →
increases XR transcription
+ Positive XYL1 copy number increase →
increases xylitol productivity
+ Positive GOX heterologous expression +
INU1 promoter swap →
increases secreted GOX expression
+ Positive LAC4 knockout →
decreases beta-galactosidase activity
+ Positive AGA1 heterologous expression →
increases alpha-galactosidase production
+ Positive