AKR point mutation: diastereoselectivity toward (5R)-1a
Positive AI-extracted, curator-verified MARXBASE-R000631
| Gene | AKR Enzyme or protein label, not a gene symbol |
|---|---|
| Gene from | K. marxianus |
| Change | point mutation |
| Effect | increases |
| Phenotype | diastereoselectivity toward (5R)-1a (enzyme activity) |
| Class | Positive |
| Host | K. marxianus |
| Strain | not stated |
Measured
| Value | 80.5 % |
|---|---|
| Size as written | from de_p ~80.5% to strict diastereoselectivity |
Evidence
Evidence sentences are not included in this release.
Paper
Rational design of Kluyveromyces marxianus ZJB14056 aldo-keto reductase KmAKR to enhance diastereoselectivity and activity.
Wang YJ; Ying BB; Shen W; Zheng RC; Zheng YG
Enzyme and microbial technology 2017 · PubMed · DOI
Cite as: MarxBase result MARXBASE-R000631, release 1.0.