MarxBaseK. marxianus metabolic engineering results

INU-ISO3 point mutation: activity on sucrose (Trp79Ala)

Positive AI-extracted, curator-verified MARXBASE-R000599

GeneINU-ISO3 Enzyme or protein label, not a gene symbol
Gene fromK. marxianus
Changepoint mutation
Effectdecreases
Phenotypeactivity on sucrose (Trp79Ala) (enzyme activity)
Class Positive
HostKomagataella pastoris
Strainnot stated
ProductSecreted enzyme (Enzymes)
Condition tagsucrose

Measured

Value98 %
Size as writtendecreased by 98 %
Metricactivity

Evidence

Evidence sentences are not included in this release.

Paper

Relevance of aromatic and polar amino acids in the specificity of Inulinase ISO3 from Kluyveromyces marxianus: A molecular dynamics approach with an experimental verification.
Trapala J; González-Andrade M; Olvera C; Cayetano-Cruz M; Sanz-Aparicio J; Jimenez-Ortega E; Bustos-Jaimes I; Montiel C
International journal of biological macromolecules 2023 · PubMed · DOI

Cite as: MarxBase result MARXBASE-R000599, release 1.0.