MNS1 deletion: LBA secretion titer
Positive AI-extracted, curator-verified MARXBASE-R000445
| Gene | MNS1 Locus tag KLMA_40509 |
|---|---|
| Gene from | K. marxianus |
| Change | deletion |
| Effect | increases |
| Phenotype | LBA secretion titer (protein production) |
| Class | Positive |
| Host | K. marxianus |
| Strain | not stated |
| Product | Other recombinant protein (Other recombinant proteins) |
Measured
| Value | 1.02 g/L 2.3-fold |
|---|---|
| Size as written | 1.02 g/L, 2.3-fold increase over parental strain |
| Metric | titer |
Conditions
| Scale | bench bioreactor |
|---|---|
| Volume (L) | 5 |
| Medium | 5-L bioreactor |
Changed together
- HMX1 knockdown (MARXBASE-R000444)
- PRB1 deletion (MARXBASE-R000446)
- SEC23 overexpression (MARXBASE-R000447)
- SAR1 overexpression (MARXBASE-R000448)
Evidence
Evidence sentences are not included in this release.
Paper
Multistep engineering of the secretory pathway for enhanced leghemoglobin expression in Kluyveromyces marxianus.
Wu X; Feng D; Chen H; Yin A; Tian T; Zhou J; Yu Y; Lu H
Bioresource technology 2026 · PubMed · DOI
Cite as: MarxBase result MARXBASE-R000445, release 1.0.