QDR2 overexpression: fumaric acid titer
Positive AI-extracted, curator-verified MARXBASE-R000411
| Gene | QDR2 Locus tag KLMA_80175 |
|---|---|
| Gene from | K. marxianus |
| Change | overexpression |
| Effect | increases |
| Phenotype | fumaric acid titer (product formation) |
| Class | Positive |
| Host | K. marxianus |
| Strain | not stated |
| Product | Fumaric acid (Organic acids) |
Measured
| Value | 2.16 g L-1 (baseline 0.26 g L-1) |
|---|---|
| Size as written | from 0.26 to 2.16 g L-1 |
| Metric | titer |
Changed together
- QDR3 overexpression (MARXBASE-R000412)
Evidence
Evidence sentences are not included in this release.
Paper
Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus.
Thornbury M; Omran RP; Kumar L; Knoops A; Abushahin R; Whiteway M; Martin VJJ
ACS synthetic biology 2025 · PubMed · DOI
Cite as: MarxBase result MARXBASE-R000411, release 1.0.