MarxBaseK. marxianus metabolic engineering results

UTR1 overexpression: xylitol production from glycerol

Positive hand-curated (gold) MARXBASE-R000027

GeneUTR1 Locus tag KLMA_30282
Gene fromK. marxianus
Changeoverexpression
Effectincreases
Phenotypexylitol production from glycerol (product formation)
Class Positive
HostK. marxianus
StrainYZB392
ProductXylitol (Sugar alcohols and polyols)
Condition tagintegrated_at_YPR1

Measured

Value3.3 g/L (baseline 2.5 g/L)
Size as written2.50 -> 3.30 g/L xylitol per 1 g/L glycerol consumed
Metrictiter

Evidence

Evidence sentences are not included in this release.

Paper

Improving glycerol utilization during high-temperature xylitol production with Kluyveromyces marxianus using a transient clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 system.
Ren L; Liu Y; Xia Y; Huang Y; Liu Y; Wang Y; Li P; Chang K; Xu D; Li F; Zhang B
Bioresource technology 2022 · PubMed · DOI

Cite as: MarxBase result MARXBASE-R000027, release 1.0.