Fluorescence-based screening for engineered aldo-keto reductase KmAKR with improved catalytic performance and extended substrate scope.

Qiu S; Xu SY; Li SF; Meng KM; Cheng F; Wang YJ; Zheng YG
Biotechnology journal 2021 · China · PubMed · DOI

Results (3 findings)

• AKR mutagenesis evolution → increases enzyme activity toward (5R)-1 + Positive
  host K. marxianus · Qiu S 2021 · details
• AKR mutagenesis evolution → increases enzyme thermostability + Positive
  host K. marxianus · Qiu S 2021 · details
• AKR mutagenesis evolution → increases enzyme activity toward 18 test substrates + Positive
  host K. marxianus · Qiu S 2021 · details

Cite this paper