Uncoupling glucose sensing from GAL metabolism for heterologous lactose fermentation in Saccharomyces cerevisiae.
Zou J; Chen X; Hu Y; Xiao D; Guo X; Chang X; Zhou L
Biotechnology letters 2021 · China · PubMed · DOI
Results (6 findings)
GAL80 deletion +
MIG1 deletion →
decreases glucose repression
+ Positive GAL80 deletion +
MIG1 deletion →
increases galactose uptake rate
+ Positive GAL80 deletion +
MIG1 deletion →
increases ethanol concentration
+ Positive GAL80 deletion +
MIG1 deletion →
increases lactose uptake rate
+ Positive GAL80 deletion +
MIG1 deletion →
increases ethanol productivity rate
+ Positive LAC4 overexpression +
LAC12 overexpression →
increases lactose uptake and conversion
+ Positive
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