CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus.

Li M; Lang X; Moran Cabrera M; De Keyser S; Sun X; Da Silva N; Wheeldon I
Biotechnology for biofuels 2021 · United States · PubMed · DOI · PMC

Results (2 findings)

• ARO4 overexpression + PHA2 overexpression + ARO7 overexpression → increases 2-PE production + Positive
  host K. marxianus · strain CBS 6556 · Li M 2021 · 684 mg/L · details
• ARO10 overexpression + EAT1 knockout → increases 2-PE production + Positive
  host K. marxianus · Li M 2021 · 766 mg/L · details

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