Engineered Kluyveromyces marxianus for pyruvate production at elevated temperature with simultaneous consumption of xylose and glucose.

Zhang B; Zhu Y; Zhang J; Wang D; Sun L; Hong J
Bioresource technology 2017 · China · PubMed · DOI

Results (5 findings)

• PDC1 knockout → decreases growth − Negative
  host K. marxianus · Zhang B 2017 · details
• MTH1 overexpression → increases growth of PDC1-disrupted strain + Positive
  host K. marxianus · Zhang B 2017 · details
• GAL2 overexpression → increases simultaneous consumption of glucose and xylose + Positive
  host K. marxianus · strain YZB058 · Zhang B 2017 · details
• GAL2 overexpression → increases pyruvate titer + Positive
  host K. marxianus · strain YZB058 · Zhang B 2017 · 29.21 g/L · details
• XYL2 overexpression → increases pyruvate production from xylose + Positive
  host K. marxianus · strain YZB053 · Zhang B 2017 · 24.62 g/L · details

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