Improving ethanol and xylitol fermentation at elevated temperature through substitution of xylose reductase in Kluyveromyces marxianus.

Zhang B; Li L; Zhang J; Gao X; Wang D; Hong J
Journal of industrial microbiology & biotechnology 2013 · China · PubMed · DOI

Results (4 findings)

• XYL1 point mutation → decreases xylose fermentation − Negative
  host K. marxianus · strain YZB015 · Zhang B 2013 · details
• XYL1 gene swap → increases ethanol titer + Positive
  host K. marxianus · strain YZB014 · Zhang B 2013 · 3.55 g/l 12.24-fold · details
• XYL1 gene swap → increases xylitol titer + Positive
  host K. marxianus · strain YZB014 · Zhang B 2013 · 11.32 g/l 2.7-fold · details
• XYL1 gene swap → increases xylose consumption + Positive
  host K. marxianus · strain YZB014 · Zhang B 2013 · 3.94-fold vs K. marxianus YHJ010 harboring KmXyl1 · details

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